Drug Synergism | NIH

The synergistic effect of drugs is when two or more drugs are combined, their overall effect is greater than the sum of their individual effects. In most cases, ...

Potentiation or synergism occurs when a mixture of two or more drugs produces a greater response than expected (i.e., greater than the sum of their individual ...

由 KR Roell 著作 · 2017 · 被引用 274 次 — The idea of synergistic interactions between drugs and chemicals has been an important issue in the biomedical world for over a century.

In medicine, describes the interaction of two or more drugs when their combined effect is greater than the sum of the effects seen when each drug is given ...

Supra-additivity or synergism occurs when a mixture of two or more drugs produces a greater response than expected (i.e., greater than the sum of their ...

由 RJ Tallarida 著作 · 2001 · 被引用 928 次 — ABSTRACT. Two drugs that produce overtly similar effects will sometimes produce exaggerated or diminished effects when used concur- rently.

由 RJ Tallarida 著作 · 2011 · 被引用 411 次 — The assessment of drug combinations for determining synergy is a quantitative pursuit. This determination requires a quantitative approach that begins with the ...

由 D Duarte 著作 · 2022 · 被引用 62 次 — The main goal when designing and evaluating drug combinations is to achieve synergistic effects by demonstrating that the combined effects are ...